Lyophilized Hirudin Power

Natural Hirudin Lyophilized Powder

Natural hirudin is a polypeptide composed of 65 amino acids with a molecular weight of 7000 Daltons, and it has been the most powerful anticoagulant substance discovered in the world up to now. It combines with the thrombin, and forms a very steady uncovalent compound substance, of which separated constant is 10-12. In comparison with raloxifene, the side effect of bleeding caused by hirudin is less. The function in anticoagulant and thrombolysis does not need the cooperation of AT-III, without consuming AT-III. The result of the emergent toxicity experiment shows: LD50>250mg/Kg.

Natural hirudin lyophilized powder is mainly composed of hirudinaria menillensis, refined by our company's patent separated, purified, frozen and dried technology (patent certificate number: ZL03113566.8), and is the most important bioactive substance in leeches' body. The product is white and light yellow monotony powder. It has many superior advantages of strong activity, little dosage, high curative effect, convenient storing and carrying, and capability of being under normal temperature.
It is the first enterprise who put natural hirudin into cosmetics in the world, and obtained several national patents for invention, patent number is ZL03140487.1.

Natural hirudin owns four unique virtues:
1. Penetrating to the deep-rooted skin directly and actively: The scientific research shows that the cells of human body commonly only absorb the substance that its molecular weight is d8000 daltons. The molecular weights of the natural substance such as hyaluronic acid, SOD and collagen in the cosmetics sold on current market are more than ten thousand and even several hundred thousand, so it is hard for the skin to absorb effectively. Fortunately, the molecular weight of natural hirudin is 7000 daltons, which can penetrate to the deep-rooted skin and be promptly absorbed and utilized by the skin cells.

2. Improve the microcirculation of the blood: Natural hirudin has the unique function in penetrating to the Capillary vessel after the skin absorbs, improving the microcirculation, enhancing the self-repair of cells, curing acnes, pigment aggradation and dent repairment. Resolve all kinds of skin problems radically in the hope of replenishing nutrition to the blood.

3. Nourishing the skin: Natural hirudin is composed of amino acid but is different from the intermediate of protein. It is possessed of the specialties of protein, but easier, less molecular weight and easier to be absorbed by organisms than protein; Because of its high bioactivity, it can play its unique functions under minim condition.

4. Helping penetrate: It can help other nutriments penetrate to the skin in order that they display their cosmetic functions. Obviously, natural hirudin is the omnipotent cosmetic additive.

5. Diminishing inflammation.

Usage: Suitable for various cosmetics including skin and hair makeup.

Petikan dari laman web www.madeinchina.com

Leeches (Lintah) are probably the most misunderstood creatures in the world.

Classification & Relationships

Leeches are related to earthworms and lugworms (Oligochaetes), and bristle worms (Polychaetes). But unlike other worms they have a sucker at each end - one for feeding, the other for hanging on while they feed. They all belong to a group of legless invertebrates (animals without a skeleton) called Annelids - "anulus" is the Latin for "ring". This means that the body is divided into separate segments (which look like rings) connected by a continuous gut, a nerve and a blood vessel. They use external bristles (chaetae) to pull themselves along in a sort of concertina-like motion.

Not all worms are Annelids. Some belong to a group called Nematodes. Many nematodes are internal parasites, often living in the guts of mammals (including humans). Leeches are external parasites.

Habitat

European leeches live in fresh water and damp places. There are a few marine leeches living in the Atlantic Ocean which prey on fishes. They can also be commonly found in tropical rainforest such as the Amazon.

Movement

On the whole leeches do not have bristles, but their flattened body allows them to swim effectively in an undulating way. They lie in wait for a passing animal of the right kind and then home in on it. They can contract their bodies to become short and stubby, or extend them to become long and thin.

Feeding habits

Some leeches are blood-suckers, and attach themselves to the skin of animals at a place where blood vessels are near the surface.The mouth end has sharp jaws to cut through the skin of it host. They inject an anti-clotting substance to stop the blood coagulating (thickening) and feed until they are full. Then they drop off to digest their meal, but the puncture bleeds for a while afterwards.

The horse leech (Haemopis sanguisuga), which can be 30 cm long when extended, does not suck horses' blood, but feeds on earthworms, and decaying flesh.

Medical uses

The medicinal leech was used in medieval times in Europe for certain illnesses because doctors believed that sucking out some of their patient's blood helped them to recover. To do this they would apply a leech or two and let them feed. Surprisingly, leeches have come back into fashion for medical use. The anti-coagulant they secrete into a wound helps to stop a scab forming, preventing the skin from sealing over too quickly. This promotes healing from the inside outwards. This is especially important where very delicate repairs have been made to torn tissue.

Fancy having two or three leeches hidden under your bandages! In films about tropical rainforest adventures the tough guys are always removing leeches from their legs.

Additional reading:

An extract from “A Sanguine Attachment 2000 Years of Leeches in Medicine “ by Roy T Sawyer Managing Director, Biopharm. Encyclopedia Britannica INC.

The leech was indispensable in 19th Century medicine for bloodletting, a practice believed to be a cure for anything from headaches to gout. Leeching was largely abandoned as medical science advanced, only occasionally being called upon to treat bruising and black eyes. However, the medicinal leech is making a comeback in modern medicine thanks in part to the work of Dr. Roy Sawyer, an American scientist who established the world's first leech farm. Based at Hendy near Swansea, South Wales, Biopharm is home to over 50,000 leeches which are supplied to hospitals and research laboratories around the world.

Thousands of patients owe the successful reattachment of body parts to miraculous technological advances in plastic and reconstructive surgery; at least some of these operations might have failed if leeches had not been reintroduced into the operating room. The appendages reattached include fingers, hands, toes, legs, ears, noses and scalps.

The pioneering use of leeches in modern plastic and reconstructive surgery can be attributed to two Slovenian surgeons, M. Derganc and F. Zdravic from Ljubljana who published a paper in the British Journal of Plastic Surgery in 1960 describing leech-assisted tissue flap surgery (in which a flap of skin is freed or rotated from an adjacent body area to cover a defect or injury). These surgeons credit their own use of leeches to a Parisian surgeon, one Philippe-Frédéric, who reported in 1836 that he had used leeches to restore circulation following reconstruction of a nose.

The rationale behind the use of leeches in surgical procedures is fairly straightforward; nonetheless, it is subject to misunderstanding, even by clinicians. The key to success is the exploitation of a unique property of the leech bite, namely, the creation of a puncture wound that bleeds literally for hours. The leech's saliva contains substances that anaesthetise the wound area, dilate the blood vessels to increase blood flow, and prevent the blood from clotting.

Microsurgeons today are adept at reattaching severed body parts, such as fingers. They usually have little trouble attaching the two ends of the arteries, because arteries are thick-walled and relatively easy to suture. The veins, however, are thin-walled and especially difficult to suture, particularly if the tissue is badly damaged. All too often the surgeon can get blood to flow in the reattached arteries but not veins. With the venous circulation severely compromised, the blood going to the reattached finger becomes congested, or stagnant; the reattached portion turns blue and lifeless and is at serious risk of being lost. It is precisely in such cases that leeches are summoned.

Links

• Worm world: Larry Leech - very delightful site for children & adults
• BBC News: Bloodsuckers hit the medical comeback trail
• BBC News: Leeches offer vein hope
• Biopharm Leeches Online Website - Suppliers of Medicinal Leeches since 1812
• Jiskha Homework Help - Science: Biology: Leeches - barebone info without the frills
• Armeniaweek: Treatment that Sucks: Leeches practice medicine at Yerevan center
• Medicinal Uses of Leeches from the Amazon and elsewhere: An Interview with Roy T. Sawyer
• Norman Miller: Science/Health/Medical: Use of leeches...

Kita Perlu Belajar

Hari ini aku tak dapat menunaikan janji aku untuk mengemaskini perkembangan pembinaan kolam ternakan lintah. Waktu yang terlalu padat tidak membenarkan aku untuk melihat perkembangan kerja pembinaan kolam. Aku berada di Hotel Seri Malaysia di Alor Setar bagi mengikuti SeminarPembangunan Usahawan Bumiputera ICT & E-Dagang Negeri Kedah.

Seminar sehari ini dianjurkan oleh Unit Pembangunan Usahawan dari Perbadanan Kemajuan Negeri Kedah (PKNK) dengan kerjasama Multimedia Super Corridor (MSC).



Insyaallah aku akan lapurkan perkembangan terkini status pembinaan kolam pada esok hari. Baiklah untuk tidak menghampakan para pengunjung aku ingin berkongsi sedikit maklumat berkenaan lintah dan penggunaannya. Semoga ianya dapat memberikan gambaran yang lebih luas kepada para pengunjung blog saya.

Lemak Lintah or Leech Fats contains enzymes of Hirudo Medicinalis (Medicinal leeches). Modern medicine uses Hirudo Medicinalis (Medicinal leeches) to treat blood clotting for skin grafts. Another lesser known of the leech is the strengthening and enlargement of the male organ. The original formula was developed by the Javanese community.

For hundred of years the native man of Malaya/Java - the elite and adepts who usually keep 4 wives - have been using a special ointment to care for their penis and maintain its virility.

This traditional method and remedy have a striking similarity with the practice of desert Arab men known for their sexual prowess as explained in Sir R F Burton's translation of Sheikh Umar el-Nefzawi book entitled "Rawd at-Tirr" or in English, The Perfumed Garden. In chapter 17 of this classical Tunisian-Arab sex-journal of the 16th century, it expounded on how the penis can be made bigger and stronger with this massage oil:

[ What is Hirudin? ]

Hirudin is a enzyme derived from the medicinal leech Hirudo Medicinalis, once used by doctors for bloodletting. Hirudin is often used following microsurgery (e.g. the replacement of a severed finger) to restore blocked or collapsed blood vessels and encourage the growth of new capillaries. The anticoagulants in the saliva of this and other species are now being investigated for the treatment and prevention of thrombosis.

This preparation is suitable for those who:

1. have problems in maintain and prolonging an erection.
2. want to increase/enhance their manhood.
3. want to avoid early release
4. want to strengthen the walls and the chambers weak urinary tract
5. develop and correct misplaced veins and poor blood flow

This oil is formulated using botanicals, herbs and oils that are well known for their special properties. The oil is further enhanced with Hirudo Medicinalis. The anticoagulant effect of Hirudin, along with the natural herbs and oils, encourages the natural process of regeneration of blood vessels along the length of the penis. If there are any obstructions in the blood vessels, the natural effect of the oil will clear them.

In cross section, the penis is divided into 3 compartments. Most of the penis is filled by 2 identical zones that are the ramrod- like corpora carvernosa (CC) that become erect when blood is trapped in thousands of sponge like spaces. The long thin compartment that runs along the underside of the penis in the middle is the corpus spongiosum (CS) that is the nerve center. When you start to get an erection, blood flows into these compartments causing the penis to enlarge. This happens because of physical or psychological stimulation. As blood enters these compartments, there is a temporary reduction in the rate and volume of blood leaving the penis.

This special oil is applied along the entire length of the penis. The massaging of the oil will improve blood flow into the corpora carvernosa (CC) resulting in more blood being trapped in its sponge like spaces. Male vigor and stamina is returned to the user as the natural process of regeneration of blood vessels allows for a better blood flow into these compartments, hence an enhanced erection. Most importantly, this oil is also used for esoteric massage to delay aging and to enhance mental faculty. Herein lies the key to an extraordinary control of ejaculation. When the veins are engorged with blood and energy, the physical exercises (included) trains the control of all major muscles along the penis. With regular use of the oil and the accompanying exercises, the user can learn to control these muscles to ejaculate at will. Thus, the can control if he wants an ejaculation, thus wasting precious energy, or to withhold the ejaculation and prolong the sexual encounter. The man with supreme control of these penile muscles can also experience multiple orgasm by with-holding ejaculation at the precise moment just before ejaculation. Through such controls, which becomes at will with practice, a man can have multiple orgasms as well as satisfy his female counterpart.